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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHD2
All Species:
17.27
Human Site:
Y104
Identified Species:
31.67
UniProt:
Q96C19
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C19
NP_077305.2
240
26697
Y104
M
E
K
M
F
K
Q
Y
D
A
G
R
D
G
F
Chimpanzee
Pan troglodytes
XP_001156210
410
44344
Y274
M
E
K
M
X
Q
Q
Y
D
A
G
R
D
G
F
Rhesus Macaque
Macaca mulatta
Q5TM25
147
16701
K46
S
D
E
D
L
L
S
K
L
E
G
F
K
E
K
Dog
Lupus familis
XP_848956
248
27200
P109
L
S
G
P
R
F
L
P
L
K
Y
D
A
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8Y0
240
26773
Y104
M
E
K
M
F
K
Q
Y
D
A
G
R
D
G
F
Rat
Rattus norvegicus
Q4FZY0
239
26741
Y103
M
E
K
M
F
K
Q
Y
D
A
G
K
D
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518105
170
19250
K68
L
G
L
K
N
M
I
K
E
V
D
E
D
F
D
Chicken
Gallus gallus
P09860
161
18412
M60
T
P
E
E
L
Q
E
M
I
D
E
V
D
E
D
Frog
Xenopus laevis
NP_001089944
202
23367
H91
K
L
G
A
P
Q
T
H
L
G
L
K
N
M
I
Zebra Danio
Brachydanio rerio
NP_001038676
233
26492
Y97
M
E
K
M
F
K
Q
Y
D
S
E
K
D
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ26
217
25068
L91
A
R
D
G
F
L
D
L
Q
E
L
K
F
M
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176294
193
22506
E90
G
L
K
A
M
M
K
E
A
D
E
D
L
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQN4
166
18399
N65
D
K
A
D
T
K
S
N
G
L
V
E
F
P
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
25.8
62
N.A.
94.1
93.3
N.A.
60
20
70.4
75
N.A.
45.8
N.A.
N.A.
53.3
Protein Similarity:
100
58.2
37.9
68.9
N.A.
97
96.6
N.A.
64.1
38.7
76.6
83.7
N.A.
60.8
N.A.
N.A.
63.7
P-Site Identity:
100
86.6
6.6
6.6
N.A.
100
93.3
N.A.
6.6
6.6
0
66.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
20
13.3
N.A.
100
100
N.A.
20
26.6
26.6
86.6
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
16
0
0
0
0
8
31
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
16
0
0
8
0
39
16
8
16
54
8
24
% D
% Glu:
0
39
16
8
0
0
8
8
8
16
24
16
0
16
8
% E
% Phe:
0
0
0
0
39
8
0
0
0
0
0
8
16
8
31
% F
% Gly:
8
8
16
8
0
0
0
0
8
8
39
0
0
39
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% I
% Lys:
8
8
47
8
0
39
8
16
0
8
0
31
8
0
8
% K
% Leu:
16
16
8
0
16
16
8
8
24
8
16
0
8
0
0
% L
% Met:
39
0
0
39
8
16
0
8
0
0
0
0
0
16
8
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
8
8
0
% N
% Pro:
0
8
0
8
8
0
0
8
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
24
39
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
8
0
0
0
0
0
0
24
0
0
8
% R
% Ser:
8
8
0
0
0
0
16
0
0
8
0
0
0
0
0
% S
% Thr:
8
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _